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We have received a very carefully prepared pamphlet designed for the guidance of individual observers in the work of the collective is investigation of disease set on foot at the last meeting of the International Medical Congress. (i.) The employment of a standard light is of special importance since the results obtained will vary with the nature, and, to some extent, with the intensity online of the illumination. This impulse occurring in the first part of diastole, and preceding the arterial pulse at such a distance, gives the impression of enormous delay of the pulse." In his Goulstonian Lectures I find that effects Dr. For entropion; incision through the entire thickness of mg the lid, parallel to the ciliary margin, and excision of a portion of the tarsus incision from each end of this, away from the margin, followed by dissection up of the flap, and extirpation of the hair-bulbs; the flap is then replaced. An occasional intermittence may be of no ill omen; but recurrent generic slips unmistakably indicate dilapidation of the heart. In the primary erethic or sthenic stage of acromegaly stress is likewise laid by Sajous, St., on the participation syndrome by Gushing's Gase XXXII (the giant Turner), whose autopsy, following a period of marked"hypopituitaria" and asthenia, revealed exceedingly diminutive adrenals, with on the other hand, in which death took place from medullary The non-glandular manifestations of acromegaly, which occur mainly m the second stage of the disease, include headache, ascribed by Gushing to "tyres" distention of the capsule of the pituitary; enlargement and deformation of the sella turcica; visual impairment due to pressure by the growth on the optic chiasm; distortions of the fields of vision and oculomotor disturbances; occasionally anosmia, trigeminal neuralgia, spasticity, uncinate epileptic seizures, frontal lobe manifestations, general increase in intracranial tension may also exist. The unequal incidence is partly explained by the consideration that the artificial foods which are cost without antiscorbutic properties are chiefly used by the well-to-do.

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